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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
6.36
Human Site:
Y1502
Identified Species:
11.67
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
Y1502
N
H
S
R
L
K
L
Y
A
Q
V
C
R
H
H
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S1480
D
L
G
P
Y
L
A
S
L
P
L
D
S
S
L
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
Y1502
N
H
S
R
L
K
L
Y
A
Q
V
C
R
H
H
Dog
Lupus familis
XP_534693
2280
250152
A1572
H
S
R
L
K
L
Y
A
Q
V
C
R
H
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
K1499
S
D
N
H
S
R
L
K
L
Y
A
Q
V
C
R
Rat
Rattus norvegicus
NP_001101807
1374
149708
L690
P
Y
L
A
T
L
Q
L
D
S
G
L
L
M
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
Y1462
C
R
Y
D
L
G
P
Y
L
A
S
Q
P
L
D
Chicken
Gallus gallus
XP_415317
2195
241321
H1488
Y
A
Q
V
C
R
H
H
L
A
P
Y
L
A
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
W1409
T
D
Q
T
L
I
D
W
L
P
K
T
I
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
L1916
S
T
Y
E
M
C
K
L
G
K
H
T
P
I
R
Honey Bee
Apis mellifera
XP_393643
1982
216109
L1298
P
I
D
D
W
F
K
L
L
G
E
N
Q
L
G
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
Y2095
E
A
F
D
R
R
G
Y
R
Y
Q
L
A
V
E
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
H443
V
W
F
T
D
V
A
H
L
P
E
A
D
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
0
100
6.6
N.A.
6.6
0
N.A.
13.3
0
N.A.
6.6
N.A.
0
0
6.6
0
P-Site Similarity:
100
13.3
100
13.3
N.A.
26.6
6.6
N.A.
13.3
13.3
N.A.
20
N.A.
20
6.6
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
8
0
0
16
8
16
16
8
8
8
8
0
% A
% Cys:
8
0
0
0
8
8
0
0
0
0
8
16
0
8
0
% C
% Asp:
8
16
8
24
8
0
8
0
8
0
0
8
8
0
8
% D
% Glu:
8
0
0
8
0
0
0
0
0
0
16
0
0
0
8
% E
% Phe:
0
0
16
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
8
0
8
8
8
0
0
0
8
% G
% His:
8
16
0
8
0
0
8
16
0
0
8
0
8
24
16
% H
% Ile:
0
8
0
0
0
8
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
0
0
8
16
16
8
0
8
8
0
0
8
0
% K
% Leu:
0
8
8
8
31
24
24
24
54
0
8
16
16
16
24
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
16
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
16
0
0
8
0
0
8
0
0
24
8
0
16
0
8
% P
% Gln:
0
0
16
0
0
0
8
0
8
16
8
16
8
0
0
% Q
% Arg:
0
8
8
16
8
24
0
0
8
0
0
8
16
0
16
% R
% Ser:
16
8
16
0
8
0
0
8
0
8
8
0
8
8
8
% S
% Thr:
8
8
0
16
8
0
0
0
0
0
0
16
0
0
8
% T
% Val:
8
0
0
8
0
8
0
0
0
8
16
0
8
8
0
% V
% Trp:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
8
16
0
8
0
8
31
0
16
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _